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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NMNAT1 All Species: 9.39
Human Site: S136 Identified Species: 15.9
UniProt: Q9HAN9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAN9 NP_073624.2 279 31932 S136 W T E T Q D S S Q K K S L E P
Chimpanzee Pan troglodytes XP_001168527 254 29013 S115 Q D S S Q K K S L E P K T K A
Rhesus Macaque Macaca mulatta XP_001118727 179 20456 S40 Q D S S Q K K S L E P K T K A
Dog Lupus familis XP_536739 279 31883 S136 A E Q R Q D F S Q K K S L E P
Cat Felis silvestris
Mouse Mus musculus Q9EPA7 285 32337 S136 W A D Q K Q D S S P Q K P Q E
Rat Rattus norvegicus Q0HA29 307 34426 P136 P Q H E N T Q P I Y Q N S N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507826 272 31049 G133 L E L K L L C G A D L L E S F
Chicken Gallus gallus XP_417605 284 32371 D139 K Q E P N R H D P I K K K N Q
Frog Xenopus laevis NP_001091188 278 32072 P137 E N S H Q D K P N S Y L Q E N
Zebra Danio Brachydanio rerio Q6PC93 304 34191 I136 P Q N E T S A I Y Q N T V N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651315 389 43777 S149 Y I N N H I N S G G G G G D D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91851 223 25149 R84 A D D W E C T R T T W T R T I
Sea Urchin Strong. purpuratus XP_783084 287 32645 A147 L R K N E P P A S N D T E V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53204 395 44891 R147 D Y E F P V H R L T K K L Q D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 62 86.3 N.A. 80.6 28.6 N.A. 63.7 69.7 60.9 26.9 N.A. 33.9 N.A. 26.1 47.3
Protein Similarity: 100 89.6 62.3 92.1 N.A. 89.4 48.5 N.A. 76.3 82 76.3 46.7 N.A. 48 N.A. 44 67.9
P-Site Identity: 100 13.3 13.3 66.6 N.A. 13.3 0 N.A. 0 13.3 20 0 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 33.3 33.3 73.3 N.A. 40 13.3 N.A. 0 13.3 20 26.6 N.A. 26.6 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 0 0 0 8 8 8 0 0 0 0 0 15 % A
% Cys: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 22 15 0 0 22 8 8 0 8 8 0 0 8 22 % D
% Glu: 8 15 22 15 15 0 0 0 0 15 0 0 15 22 8 % E
% Phe: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 8 8 8 8 8 8 0 0 % G
% His: 0 0 8 8 8 0 15 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 8 8 8 0 0 0 0 8 % I
% Lys: 8 0 8 8 8 15 22 0 0 15 29 36 8 15 8 % K
% Leu: 15 0 8 0 8 8 0 0 22 0 8 15 22 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 15 15 15 0 8 0 8 8 8 8 0 22 8 % N
% Pro: 15 0 0 8 8 8 8 15 8 8 15 0 8 0 15 % P
% Gln: 15 22 8 8 36 8 8 0 15 8 15 0 8 15 8 % Q
% Arg: 0 8 0 8 0 8 0 15 0 0 0 0 8 0 0 % R
% Ser: 0 0 22 15 0 8 8 43 15 8 0 15 8 8 0 % S
% Thr: 0 8 0 8 8 8 8 0 8 15 0 22 15 8 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 8 % V
% Trp: 15 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 0 0 8 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _